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6. METABOLIC & FAT LOSS

Physics vs. Biology. Thermodynamics still apply, but peptides allows us to manipulate the efficiency of the engine.

Module 6

Insulin Sensitivity

Lipolysis

Mitochondrial Health

Core Metric: Metabolic Flexibility

The Metabolic Renaissance.

We have entered the era of the "Triple Agonist" and "Mitochondrial Mimetics". Metabolic health is no longer just about calories—it's about Signaling Efficiency. From Retatrutide to MOTS-c, this module covers the mechanics of energy.

The Strategic Split

Incretin Mimetics

Appetite & Signaling

Focus: Reducing intake and stabilizing glucose.

Primary Tool: GLP-1 / GIP / GCG
Mechanism: Delayed gastric emptying & central satiety.
Side Effect: Nausea, muscle loss if protein is low.

Metabolic Accelerators

Output & Flux

Focus: Increasing calorie expenditure & efficiency.

Primary Tool: 5-Amino-1MQ / MOTS-c
Mechanism: NNMT inhibition & exercise mimicry.
Benefit: Muscle sparing & mitochondrial density.

Chapter Directory

6.1 Philosophy

6.2 Tesofensine

6.3 5-Amino-1MQ

6.4 MOTS-c

6.5 Retatrutide

6.6 Yearly Cycle

🔗 Related Tools

Previous Module: Mental

Related Peptides

Semaglutide

Tirzepatide

Retatrutide

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Peptide Assistant

Command Center
BETA

Learning Journey

6. METABOLIC & FAT LOSS

The Metabolic Renaissance.

The Strategic Split

Appetite & Signaling

Output & Flux

Chapter Directory

6.1 Philosophy

6.2 Tesofensine

6.3 5-Amino-1MQ

6.4 MOTS-c

6.5 Retatrutide

6.6 Yearly Cycle

🔗 Related Tools

6. METABOLIC & FAT LOSS

The Metabolic Renaissance.

The Strategic Split

Appetite & Signaling

Output & Flux

Chapter Directory

6.1 Philosophy

6.2 Tesofensine

6.3 5-Amino-1MQ

6.4 MOTS-c

6.5 Retatrutide

6.6 Yearly Cycle

🔗 Related Tools

Peptide Assistant

Command Center BETA

Learning Journey

The Metabolic Renaissance.

The Strategic Split

Appetite & Signaling

Output & Flux

Chapter Directory

6.1 Philosophy

6.2 Tesofensine

6.3 5-Amino-1MQ

6.4 MOTS-c

6.5 Retatrutide

6.6 Yearly Cycle

🔗 Related Tools

The Metabolic Renaissance.

The Strategic Split

Appetite & Signaling

Output & Flux

Chapter Directory

6.1 Philosophy

6.2 Tesofensine

6.3 5-Amino-1MQ

6.4 MOTS-c

6.5 Retatrutide

6.6 Yearly Cycle

🔗 Related Tools

Command Center
BETA