Peptide Engine | The Complete Guide to Peptides, Biohacking & Longevity Medicine

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Goal

Dose

Frequency

Libido Boost

100-200mcg

As needed (1-2hr before)

TRT Support

100mcg

2x Daily

Fertility

50-100mcg

2-3x Daily (Pulsatile)

PCT

100mcg

2x Daily (4-6 weeks)

The Upstream Regulator.

Kisspeptin is the "master switch" of the HPG axis. It stimulates GnRH neurons to release LH/FSH. Unlike exogenous Testosterone (which shuts you down), Kisspeptin activates natural production.

🔬 The HPG Axis

1. KISSPEPTINHypothalamus → GnRH Neurons

2. Pituitary (LH / FSH)Signals the Gonads

3. Gonads (Testosterone + Sperm)Downstream Output

🎯 Kisspeptin vs. TRT

❌ Exogenous TRT

• Shuts down natural production
• Testicular Atrophy
• Fertility Impairment

✅ Kisspeptin

• Stimulates natural production
• Preserves testicular function
• Enhances Fertility

💉 Dosing Protocols

Goal	Dose	Frequency
Libido Boost	100-200mcg	As needed (1-2hr before)
TRT Support	100mcg	2x Daily
Fertility	50-100mcg	2-3x Daily (Pulsatile)
PCT	100mcg	2x Daily (4-6 weeks)

🔗 Related Tools

Previous: Sexual Function

← Chapter 7.7

Next: GLP-1 Protocols

Chapter 8.1 →

Peptide Assistant

Command Center
BETA

Learning Journey

Kisspeptin-10: The Master Switch

🔬 The HPG Axis

🎯 Kisspeptin vs. TRT

💉 Dosing Protocols

🔗 Related Tools

Kisspeptin-10: The Master Switch

🔬 The HPG Axis

🎯 Kisspeptin vs. TRT

💉 Dosing Protocols

🔗 Related Tools

Peptide Assistant

Command Center BETA

Learning Journey

🔬 The HPG Axis

🎯 Kisspeptin vs. TRT

💉 Dosing Protocols

🔗 Related Tools

🔬 The HPG Axis

🎯 Kisspeptin vs. TRT

💉 Dosing Protocols

🔗 Related Tools

Command Center
BETA